Discrimination of collagen in normal and pathological skin dermis through second-order susceptibility microscopy
نویسندگان
چکیده
منابع مشابه
In vivo visualization of dermal collagen fiber in skin burn by collagen-sensitive second-harmonic-generation microscopy.
Optical assessment of skin burns is possible with second-harmonic-generation (SHG) microscopy due to its high sensitivity to thermal denaturation of collagen molecules. In contrast to previous studies that were performed using excised tissue specimens ex vivo, in vivo observation of dermal collagen fibers in living rat burn models with SHG microscopy is demonstrated. Changes in signal vanishing...
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ژورنال
عنوان ژورنال: Optics Express
سال: 2009
ISSN: 1094-4087
DOI: 10.1364/oe.17.011161